Optic Disc Pit Maculopathy

By Andrew Chang, MBBS, PhD, FRANZCO; and Ran Wan, MBBS, PhD, BOptom
 

A 35-year-old woman presented with a 2-month history of central vision loss in her right eye (OD). At presentation, VA was 20/200 OD and 20/20 in the left eye. Anterior segment examination was unremarkable. Dilated retinal examination showed marked elevation at the macula (main figure) and a temporal optic disc pit OD (inset left). Spectral domain OCT (Spectralis, Heidelberg) confirmed the macular schisis extending from the optic pit with a defect in the inner segment/outer segment junction at the fovea (inset right, top).

A three-port pars plana vitrectomy with hyaloid and internal limiting membrane (ILM) peeling followed by fluid-air exchange was performed. At the 6-month follow-up visit, the macular hole was closed, and VA was 20/30 OD (inset right, bottom).

Optic disc pits are rare congenital defects thought to reflect failure of fetal fissure closure during embryogenesis. Serous macular detachment is a visually debilitating complication of optic disc pit affecting 25% to 75% of patients with optic disc pit.1-4 There is no clear consensus on the management of optic disc pit–associated maculopathy. Treatment approaches for symptomatic maculopathy include combinations of barricade laser, vitrectomy, ILM peeling, and gas tamponade. In this patient, successful anatomic and functional outcomes were achieved after vitrectomy, ILM peeling, and gas tamponade.

1. Bonnet M. Serous macular detachment associated with optic nerve pits. Graefes Arch Clin Exp Ophthalmol. 1991;229(6):526-532.

2. Georgalas I, Ladas I, Georgopoulos G, Petrou P. Optic disc pit: a review. Graefes Arch Clin Exp Ophthalmol. 2011;249(8):1113-1122.

3. Brown GC, Augsburger JJ. Congenital pits of the optic nerve head and retinochoroidal colobomas. Can J Ophthalmol. 1980;15(3):144-146.

4. Gordon R, Chatfield RK. Pits in the optic disc associated with macular degeneration. Br J Ophthalmol. 1969;53(7):481-489.

Section Editor Manish Nagpal, MS, DO, FRCS(Edin)
• Senior Consultant, Retina and Vitreous Services, Retina Foundation, Ahmedabad, India
drmanishnagpal@yahoo.com

Andrew Chang, MBBS, PhD, FRANZCO
• Director Sydney Retina Clinic; Head of Retinal Unit, Sydney Eye Hospital; Associate Professor, Sydney University Medical School, all in Sydney, Australia
• Email: achang@sydneyretina.com.au
• Financial disclosures: None

Ran Wan, MBBS, PhD, BOptom
• Research Fellow, Sydney Retina Clinic, Sydney, Australia
• Email: wanran@hotmail.com
• Financial disclosure: None


To share an image, contact Dr. Nagpal at drmanishnagpal@yahoo.com.
Note: Images should be 400 dpi or higher and at least 10 inches wide.

 

Contact Info

Bryn Mawr Communications LLC
1008 Upper Gulph Road, Suite 200
Wayne, PA 19087

Phone: 484-581-1800
Fax: 484-581-1818

Scott Krzywonos
Editor-in-Chief
484-581-1880
skrzywonos@bmctoday.com

Janet Burk
Publisher
214-394-3551
jburk@bmctoday.com

About Retina Today

Retina Today is a publication that delivers the latest research and clinical developments from areas such as medical retina, retinal surgery, vitreous, diabetes, retinal imaging, posterior segment oncology and ocular trauma. Each issue provides insight from well-respected specialists on cutting-edge therapies and surgical techniques that are currently in use and on the horizon.